They collectively have more than 500 autonomous vehicles already in operation. Cruise and Waymo have been running experimental services limited by times and geographic areas within San Francisco. The approval “marks the true beginning of our commercial operations in San Francisco,” said Tekedra Mawakana, Waymo co-CEO, in a prepared statement. San Francisco is important as both a symbolic hub of tech and, with hundreds of AVs already in operation, the largest test lab for the experimental cars. The vehicles, with empty driver seats and self-turning steering wheels, have become a common sight around San Francisco.